Conditions Required for Hardy-Weinberg Equilibrium (College Board AP Biology)

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Conditions for Hardy-Weinberg Equilibrium

  • The Hardy-Weinberg principle states that if certain conditions are met then the allele frequencies of a gene within a population will not change from one generation to the next
  • There are seven conditions or assumptions that must be met for the Hardy-Weinberg principle to hold true
  • The Hardy-Weinberg equation allows for the calculation of allele and genotype frequencies within populations
  • It also allows for predictions to be made about how these frequencies will change in future generations

Conditions for Hardy-Weinberg equilibrium

  • For the Hardy-Weinberg principle to be correctly applied to a population a series of conditions, or assumptions, need to be met
    • Organisms are diploid
    • Organisms reproduce by sexual reproduction only
    • There is no overlap between generations, i.e. parents do not mate with offspring
    • Mating is random
    • The population is large
    • There is no migration, mutation, or selection
      • This would mean no individuals entering the population (immigration) or leaving (emigration)
      • Selection refers to both natural and artificial selection
    • Allele frequencies are equal in both sexes
  • The Hardy-Weinberg principle can be useful when building models and making predictions, but the assumptions listed are very rarely, if ever, all present in nature
  • Despite this, the Hardy-Weinberg equilibrium concept can provide a useful null hypothesis when evaluating the effects of genetic changes

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Phil

Author: Phil

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.