Lowering of Activation Energy (College Board AP Biology)

Revision Note

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Biology Project Lead

Enzymes as Biological Catalysts

  • Enzymes are biological catalysts
    • ‘Biological’ because they function in living systems
    • ‘Catalysts’ because they speed up the rate of chemical reactions without being used up or changed

Graph to Show How Enzymes Lower Activation Energy

The activation energy of a chemical reaction is lowered by a catalystThe activation energy of a chemical reaction is lowered by the presence of a catalyst (ie. an enzyme)

Enzymes work by lowering the activation energy of a reaction

  • All chemical reactions are associated with energy changes
  • For a reaction to proceed there must be enough activation energy
  • Activation energy is the amount of energy needed by the substrate to become just unstable enough for a reaction to occur and for products to be formed
    • Enzymes speed up chemical reactions because they influence the stability of bonds in the reactants
    • The destabilization of bonds in the substrate makes it more reactive
  • Enzymes work by lowering the activation energy of a reaction and in doing so they provide an alternative energy pathway

Exam Tip

Don't forget that enzymes are proteins and so anything that could denature a protein, extremes of heat, temperature, pH etc. would also denature an enzyme.

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Phil

Author: Phil

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.